Efficacy and Safety of Endoscopic Ultrasound-guided Ethanol Ablation Therapy for Pancreatic Neuroendocrine Tumors

Acta Med Okayama. 2016 Aug;70(4):313-6. doi: 10.18926/AMO/54511.


Recently, endoscopic ultrasonography (EUS)-guided ethanol ablation for small pancreatic neuroendocrine tumors (p-NETs) has been reported. However, the efficacy and safety of the technique remain unclear. We have launched a prospective pilot study of EUS-guided ethanol ablation for p-NETs. The major eligibility criteria are the presence of a pathologically diagnosed grade (G) 1 or G2 p-NET, a tumor size of 2cm, and being a poor candidate for surgery. A total of 5 patients will be treated. The primary endpoint will be the complete ablation rate at 1 month after treatment.

MeSH terms

  • Ablation Techniques / methods*
  • Clinical Protocols
  • Endosonography / methods*
  • Ethanol / pharmacology*
  • Humans
  • Neuroendocrine Tumors / therapy*
  • Pancreatic Neoplasms / therapy*
  • Pilot Projects


  • Ethanol