Androgenetic Alopecia: An Update of Treatment Options

Drugs. 2016 Sep;76(14):1349-64. doi: 10.1007/s40265-016-0629-5.


Androgenetic alopecia (AGA) is characterized by a non-scarring progressive miniaturization of the hair follicle in predisposed men and women with a pattern distribution. Although AGA is a very prevalent condition, approved therapeutic options are limited. This article discusses the current treatment alternatives including their efficacy, safety profile, and quality of evidence. Finasteride and minoxidil for male androgenetic alopecia and minoxidil for female androgenetic alopecia still are the therapeutic options with the highest level evidence. The role of antiandrogens for female patients, the importance of adjuvant therapies, as well as new drugs and procedures are also addressed.

Publication types

  • Review

MeSH terms

  • Alopecia / drug therapy*
  • Androgen Antagonists / pharmacology*
  • Androgen Antagonists / therapeutic use*
  • Animals
  • Female
  • Finasteride / pharmacology
  • Finasteride / therapeutic use
  • Humans
  • Male
  • Minoxidil / pharmacology
  • Minoxidil / therapeutic use


  • Androgen Antagonists
  • Finasteride
  • Minoxidil