Is chronic periodontitis premature in systemic lupus erythematosus patients?

Clin Rheumatol. 2017 Mar;36(3):713-718. doi: 10.1007/s10067-016-3385-8. Epub 2016 Aug 24.


The aim of this study was to compare the frequency and severity of chronic periodontitis (CP) in systemic lupus erythematosus (SLE) patients with individuals without rheumatic diseases. Seventy-five patients with SLE were compared to 75 individuals without rheumatic diseases (control group) matched for age, educational level, and income. The activity of SLE was assessed with the Systemic Lupus Erythematosus Disease Activity Index 2000. Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index for Systemic Lupus Erythematosus evaluated SLE-related damage. Dental evaluation included measuring plaque index and parameters of periodontal disease (probing depth, clinical attachment level, and bleeding on probing). Fifty-one (68 %) SLE patients and 42 (56 %) control individuals had CP (p = 0.13). Periodontal status was similar in both groups. Considering only individuals with CP, SLE patients were younger than controls (40.7 ± 9.8 versus 46.14 ± 12.5 years of age, p = 0.02). CP was not associated with activity or therapeutics in SLE patients. Severity of periodontal parameters was similar in SLE patients and control subjects; however, CP occurred earlier in SLE patients.

Keywords: Chronic periodontitis; Comorbid diseases; Periodontal diseases; Systemic lupus erythematosus.

MeSH terms

  • Adult
  • Chronic Periodontitis / diagnosis
  • Chronic Periodontitis / epidemiology*
  • Comorbidity
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / epidemiology*
  • Male
  • Middle Aged
  • Prevalence
  • Severity of Illness Index