Potential Swimming Motility Variation by AcrR in Escherichia coli

J Microbiol Biotechnol. 2016 Oct 28;26(10):1824-1828. doi: 10.4014/jmb.1607.07058.

Abstract

AcrR, the toxic-compounds-response regulator, regulates motility in microorganisms, presumably to escape from toxic environments. In this study, the genome-wide target genes of AcrR were investigated in a ΔacrR mutant strain by microarray analysis. In the absence of AcrR, the transcription of most flagella/motility genes was highly increased. In addition, flagella formation was increased in this mutant strain. Motility assays revealed that AcrR modulates swimming motility, but not swarming.

Keywords: AcrR; flagella; motility; swarming; swimming.

MeSH terms

  • Cell Movement / genetics*
  • Escherichia coli / genetics*
  • Escherichia coli / physiology*
  • Escherichia coli Proteins / genetics*
  • Flagella / genetics
  • Flagella / physiology
  • Mutation / genetics*
  • Mutation / physiology
  • Repressor Proteins / genetics*

Substances

  • AcrR protein, E coli
  • Escherichia coli Proteins
  • Repressor Proteins