Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 19 (4), 328-31

In Vitro Evaluation of Remineralization Efficacy of Different Calcium- And Fluoride-Based Delivery Systems on Artificially Demineralized Enamel Surface

Affiliations

In Vitro Evaluation of Remineralization Efficacy of Different Calcium- And Fluoride-Based Delivery Systems on Artificially Demineralized Enamel Surface

Aparajita Gangrade et al. J Conserv Dent.

Abstract

Background: Caries is the most common dental disease facing the world population. Caries can be prevented by remineralizing early enamel lesions.

Aim: To evaluate remineralization efficacy of stannous fluoride (SnF2), casein phosphopeptide-amorphous calcium phosphate with fluoride (CPP-ACPF) and calcium sucrose phosphate (CaSP).

Materials and methods: Fifty enamel samples were taken; they were divided into five groups (n = 10). Demineralization was carried out with Groups A, B, C, and E. Remineralization was carried out with Groups A, B, and C for 7 days using SnF2, CPP-ACPF, and CaSP, respectively. In Group D, no surface treatment was carried out, to mark as positive control whereas Group E was kept as negative control with only surface demineralization of enamel. Enamel microhardness was tested using Vickers's microhardness tester after 7 day remineralization regime.

Statistical analysis: One-way analysis of variance and post hoc Tukey tests were performed.

Results: The mean microhardness values in descending order: Positive control > SnF2> CaSP > CPP-ACPF > negative control.

Conclusion: All remineralizing agents showed improved surface remineralization. However, complete remineralization did not occur within 7 days. SnF2 showed the highest potential for remineralization followed by CaSP and CPP-ACPF.

Keywords: Calcium sucrose phosphate; caries prevention; casein phosphopeptide-amorphous calcium phosphate with fluoride; microhardness; remineralization; stannous fluoride.

Similar articles

See all similar articles

Cited by 4 PubMed Central articles

References

    1. Patil N, Choudhari S, Kulkarni S, Joshi SR. Comparative evaluation of remineralizing potential of three agents on artificially demineralized human enamel: An in vitro study. J Conserv Dent. 2013;16:116–20. - PMC - PubMed
    1. Lata S, Varghese NO, Varughese JM. Remineralization potential of fluoride and amorphous calcium phosphate-casein phospho peptide on enamel lesions: An in vitro comparative evaluation. J Conserv Dent. 2010;13:42–6. - PMC - PubMed
    1. Jayarajan J, Janardhanam P, Jayakumar P. Deepika. Efficacy of CPP-ACP and CPP-ACPF on enamel remineralization – An in vitro study using scanning electron microscope and DIAGNOdent. Indian J Dent Res. 2011;22:77–82. - PubMed
    1. Sargod SS, Bhat SS, Hegde S, Karunakaran R. Remineralization potential using calcium sucrose phosphate (EnaFix) on artificial carious lesion: A polaroid microscopic study. Indian J Appl Res. 2015;5:421–3.
    1. Shetty S, Hegde MN, Bopanna TP. Enamel remineralization assessment after treatment with three different remineralizing agents using surface microhardness: An in vitro study. J Conserv Dent. 2014;17:49–52. - PMC - PubMed
Feedback