Low digit ratio (2D:4D) in male suicide victims

J Neural Transm (Vienna). 2016 Dec;123(12):1499-1503. doi: 10.1007/s00702-016-1608-4. Epub 2016 Aug 26.

Abstract

Although women attempt suicides equally or more often than men do, men are more likely to die of suicide than women (sex paradox of suicidal behavior). Furthermore, the male traits of aggression and impulsivity predict suicide completion. Here, we studied the second-to-fourth-finger length ratio (2D:4D), a proxy for prenatal androgen exposure, in 46 suicide corpses and 25 non-suicide corpses. We report significantly lower 2D:4D in male suicide corpses than non-suicide corpses (p = .030, partial η 2 = .147). There was no significant association between 2D:4D and the suicide method. Our findings indicate increased risk of suicide following higher prenatal androgen exposure in males. The results may improve future efforts to predict and prevent suicides.

Keywords: 2D:4D; Prenatal androgen exposure; Second-to-fourth-finger length ratio; Suicide.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Analysis of Variance
  • Anthropometry
  • Female
  • Fingers / pathology*
  • Functional Laterality
  • Humans
  • Male
  • Middle Aged
  • Sex Characteristics*
  • Substance-Related Disorders / pathology*
  • Substance-Related Disorders / psychology*
  • Suicide* / statistics & numerical data