Repair of anomalous coronary artery from the pulmonary artery: A-signal center 20-year experience

Int J Cardiol. 2016 Nov 15:223:625-629. doi: 10.1016/j.ijcard.2016.08.221. Epub 2016 Aug 13.


Background: Anomalous origin of coronary artery from the pulmonary artery (ACAPA) is a rare congenital coronary malformation with a high mortality whether in infants or adult patients. This study reviews 20years of surgical treatment in a single center and aims to establish the optimal surgical strategies for this rare pathology.

Methods and results: From April 1994 to March 2015, 96 consecutive patients aged from 3months to 60years underwent coronary repair surgery. The surgical procedures included ligation (3 cases), ligation along with CABG (6 cases), transpulmonary baffling (Takeuchi Procedure, 14 cases) and directly implantation of the anomalous coronary artery (ACA) into the aorta (73 cases). Postoperative extracorporeal mechanical circulatory support (ECMO) was necessary in 4 cases. Mitral valve repair was performed in 40 patients with moderate or severe mitral regurgitation (MR). Mitral replacement was performed in one patient with severe MR. There were one early and two late deaths. One patient underwent a second operation because Baffle leaks. During mean 10.45±8.96year follow-up (1month-18years), both early and late improvement of left ventricular function was observed in most patients (8 patients lost of follow-up).

Conclusions: The establishment of a two-coronary system is the main goal of surgical therapy today. In different procedures, the direct implantation of the ACA into the ascending aorta is the best method and has good long-term results. ECMO as a bridge to recovery that will play an integral part in moderns' surgical treatment.

Keywords: Anomalous coronary artery from the pulmonary artery; Congenital heart disease; Coronary anomaly; Surgical treatment.

MeSH terms

  • Adolescent
  • Adult
  • Cardiac Surgical Procedures / methods*
  • Child
  • Child, Preschool
  • Coronary Vessel Anomalies / diagnostic imaging
  • Coronary Vessel Anomalies / surgery*
  • Extracorporeal Membrane Oxygenation / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Pulmonary Artery / abnormalities*
  • Pulmonary Artery / diagnostic imaging
  • Pulmonary Artery / surgery*
  • Retrospective Studies
  • Young Adult