Successful treatment with weekly high-dose erlotinib against meningeal metastases from epidermal growth factor receptor (EGFR)-mutated lung adenocarcinoma

Ryota Kanemaru; Yoshiteru Morio; Hidenori Takekawa; Hitomi Jo; Fumiko Kasuga; Ryo Koyama; Satomi Shiota; Tetsutaro Nagaoka; Kazuhisa Takahashi

doi:10.1016/j.resinv.2016.04.001

Successful treatment with weekly high-dose erlotinib against meningeal metastases from epidermal growth factor receptor (EGFR)-mutated lung adenocarcinoma

Respir Investig. 2016 Sep;54(5):372-5. doi: 10.1016/j.resinv.2016.04.001. Epub 2016 Jun 6.

Authors

Ryota Kanemaru¹, Yoshiteru Morio², Hidenori Takekawa³, Hitomi Jo⁴, Fumiko Kasuga⁵, Ryo Koyama⁶, Satomi Shiota⁷, Tetsutaro Nagaoka⁸, Kazuhisa Takahashi⁹

Affiliations

¹ Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-Ku, Tokyo 113-8431, Japan. Electronic address: rkanema@juntendo.ac.jp.
² Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-Ku, Tokyo 113-8431, Japan. Electronic address: ymorio@juntendo.ac.jp.
³ Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-Ku, Tokyo 113-8431, Japan. Electronic address: htakekaw@juntendo.ac.jp.
⁴ Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-Ku, Tokyo 113-8431, Japan. Electronic address: jo@juntendo.ac.jp.
⁵ Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-Ku, Tokyo 113-8431, Japan. Electronic address: ffujiwa@juntendo.ac.jp.
⁶ Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-Ku, Tokyo 113-8431, Japan. Electronic address: rkoyama@juntendo.ac.jp.
⁷ Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-Ku, Tokyo 113-8431, Japan. Electronic address: sshiota@juntendo.ac.jp.
⁸ Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-Ku, Tokyo 113-8431, Japan. Electronic address: jnagaoka@juntendo.ac.jp.
⁹ Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-Ku, Tokyo 113-8431, Japan. Electronic address: kztakaha@juntendo.ac.jp.

PMID: 27566387
DOI: 10.1016/j.resinv.2016.04.001

No abstract available

Publication types

Case Reports

MeSH terms

Adenocarcinoma / genetics*
Adenocarcinoma / pathology*
ErbB Receptors / genetics*
Erlotinib Hydrochloride / administration & dosage*
Female
Humans
Lung Neoplasms / genetics*
Lung Neoplasms / pathology*
Meningeal Neoplasms / drug therapy*
Meningeal Neoplasms / secondary
Middle Aged
Mutation*

Substances

Erlotinib Hydrochloride
ErbB Receptors