Diabetes in Pregnancy

J Obstet Gynaecol Can. 2016 Jul;38(7):667-679.e1. doi: 10.1016/j.jogc.2016.04.002. Epub 2016 May 12.


Objective: This guideline reviews the evidence relating to the diagnosis and obstetrical management of diabetes in pregnancy.

Outcomes: The outcomes evaluated were short- and long-term maternal outcomes, including preeclampsia, Caesarean section, future diabetes, and other cardiovascular complications, and fetal outcomes, including congenital anomalies, stillbirth, macrosomia, birth trauma, hypoglycemia, and long-term effects.

Evidence: Published literature was retrieved through searches of PubMed and the Cochrane Library using appropriate controlled vocabulary (MeSH terms "diabetes" and "pregnancy"). Where appropriate, results were restricted to systematic reviews, randomized control trials/controlled clinical trials, and observational studies. There were no date limits, but results were limited to English or French language materials.

Values: The quality of evidence was rated using the criteria described in the Report of the Canadian Task Force on Preventive Health Care (Table 1).

Summary statements: Recommendations It is recognized that the use of different diagnostic thresholds for the "preferred" and "alternative" strategies could cause confusion in certain settings. Despite this, the committee has identified the importance of remaining aligned with the current Canadian Diabetes Association 2013 guidelines as being a priority. It is thus recommended that each care centre strategically align with 1 of the 2 strategies and implement protocols to ensure consistent and uniform reporting of test results.

Keywords: Diabetes; pregnancy; stillbirth.

Publication types

  • Practice Guideline
  • Review
  • Comment

MeSH terms

  • Adult
  • Blood Glucose
  • Breast Feeding
  • Canada
  • Diabetes Mellitus
  • Diabetes, Gestational* / diagnosis
  • Diabetes, Gestational* / therapy
  • Female
  • Humans
  • Hyperglycemia / complications
  • Pregnancy
  • Pregnancy in Diabetics* / diagnosis
  • Pregnancy in Diabetics* / therapy
  • Stillbirth
  • Young Adult


  • Blood Glucose