Surg Oncol Clin N Am. 2016 Oct;25(4):775-88. doi: 10.1016/j.soc.2016.05.008. Epub 2016 Jul 30.


Myxofibrosarcoma is a unique subtype of soft tissue sarcoma with a locally infiltrative behavior. High-quality MRI imaging is critical for preoperative planning. Wide surgical resection with a 2 cm soft tissue margin is the mainstay of treatment and can require complex vascular and plastic surgery reconstruction. Local recurrence is common, and a subset of patients with higher-grade lesions will develop distant metastases. Radiation may be beneficial in reducing local recurrence.

Keywords: MRI; Myxofibrosarcoma; Recurrence; Surgery.

Publication types

  • Review

MeSH terms

  • Fibrosarcoma / diagnostic imaging*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Neoplasm Recurrence, Local / diagnosis
  • Neoplasm Recurrence, Local / diagnostic imaging*
  • Sarcoma / classification*
  • Soft Tissue Neoplasms / diagnostic imaging*