[Predominance of crossed optic nerve fibers is a characteristic of albinism, but not of dissociated vertical deviation]

Fortschr Ophthalmol. 1989;86(3):253-5.
[Article in German]


We examined eight patients with dissociated vertical deviation (DVD) for evidence of misrouting in the visual pathway, using visually evoked potentials. Full-field monocular pattern-onset chequerboard stimulation was employed. The visually evoked potentials were recorded from both occipital lobes. Their differential activity during stimulation of the right eye was compared with that obtained during stimulation of the left eye. In contrast to an earlier report, a predominance of the crossed projection was not found in any of the DVD cases. The results in eight normal control subjects were similar, unlike our findings in eight albino patients (predominance of crossed projection: a relative positivity over the contralateral hemisphere about 100 ms after pattern-onset). Possible artifacts are discussed that may have led to the earlier assumption of misrouting in DVD patients.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Albinism / physiopathology*
  • Child
  • Dominance, Cerebral / physiology*
  • Evoked Potentials, Visual*
  • Humans
  • Middle Aged
  • Optic Nerve / physiopathology*
  • Strabismus / physiopathology*
  • Visual Cortex / physiopathology
  • Visual Pathways / physiopathology