Congenital long QT syndrome inducing 2:1 atrioventricular block: early detection in fetal life

P Presbitero; L Mangiardi; R Antolini

doi:10.1016/0167-5273(89)90049-1

Congenital long QT syndrome inducing 2:1 atrioventricular block: early detection in fetal life

Int J Cardiol. 1989 Jul;24(1):109-12. doi: 10.1016/0167-5273(89)90049-1.

Authors

P Presbitero¹, L Mangiardi, R Antolini

Affiliation

¹ Istituto di Medicina e Chirurgia Cardiovascolare, Università di Torino, Italy.

PMID: 2759746
DOI: 10.1016/0167-5273(89)90049-1

Abstract

A case is reported of congenital long QT interval associated with fixed 2:1 atrioventricular block. The bradycardia was detected at 16 weeks of gestational age. The atrioventricular block was due to an extremely delayed ventricular repolarization. Early detection of bradycardia in fetal life and the demonstration of a normal positive correlation between QT duration and ventricular rate suggest that, in this case, the syndrome may be due to an anomaly of the myocardial cells rather than to imbalance of the sympathetic nervous system.

MeSH terms

Arrhythmias, Cardiac / diagnosis*
Echocardiography*
Female
Fetal Diseases / diagnosis*
Heart Block / diagnosis*
Humans
Long QT Syndrome / congenital
Long QT Syndrome / diagnosis*
Pregnancy