Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Jun;264(6):1035-1050.
doi: 10.1007/s00415-016-8263-4. Epub 2016 Sep 7.

Vaccines and Multiple Sclerosis: A Systematic Review

Affiliations
Review

Vaccines and Multiple Sclerosis: A Systematic Review

Mia Topsøe Mailand et al. J Neurol. .

Abstract

Vaccinations are often the most effective tool against some disease known to mankind. This study offers a literature review on the role of vaccines regarding the risk of developing multiple sclerosis (MS) and MS relapse. The method used in this study is a systematic literature review on the database PubMed. The study found no change in risk of developing multiple sclerosis (MS) after vaccination against hepatitis B virus, human papillomavirus, seasonal influenza, measles-mumps-rubella, variola, tetanus, Bacillus Calmette-Guérin (BCG), polio, or diphtheria. No change in risk of relapse was found for influenza. Further research is needed for the potential therapeutic use of the BCG vaccine in patients in risk of developing MS and for the preventive potential of the tetanus and diphtheria vaccine.

Keywords: Immunization; Multiple sclerosis; Vaccination.

Similar articles

See all similar articles

Cited by 10 articles

See all "Cited by" articles

References

    1. Ann N Y Acad Sci. 1965 Mar 31;122:457-66 - PubMed
    1. Mult Scler. 1997 Aug;3(4):243-7 - PubMed
    1. J Neurol Sci. 1998 Jul 15;159(1):51-3 - PubMed
    1. Vaccine. 2007 Aug 1;25(31):5938-43 - PubMed
    1. Arch Neurol. 2003 Apr;60(4):504-9 - PubMed
Feedback