Milk hypersensitivities: where is the grey line regarding their dietary management?

Eur Ann Allergy Clin Immunol. 2016 Sep;48(5):164-73.


The proportion of people suffering or reporting to have a hypersensitivity caused by cow's milk consumption is increasing, and even health professionals often face difficulties into elaborating properly with a milk reaction due to misdiagnosis. The scope of this review is to present literature data that lead into putting the border line between cow's milk allergy and cow's milk intolerance, mainly focusing on how the different pathophysiology leads to their different dietary diagnosis and management.

Keywords: calcium supplementation; cow’s milk allergy; cow’s milk intolerance; dietary management; vitamin D.

Publication types

  • Review

MeSH terms

  • Calcium / administration & dosage
  • Diagnostic Errors
  • Dietary Supplements
  • Humans
  • Lactose Intolerance / diagnosis
  • Lactose Intolerance / diet therapy*
  • Lactose Intolerance / epidemiology
  • Lactose Intolerance / physiopathology
  • Milk Hypersensitivity / diagnosis
  • Milk Hypersensitivity / diet therapy*
  • Milk Hypersensitivity / epidemiology
  • Milk Hypersensitivity / physiopathology
  • Nutritional Status
  • Predictive Value of Tests
  • Risk Factors
  • Treatment Outcome


  • Calcium