Study of Association of Atherosclerotic Risk Factors and Metabolic Syndrome in Patients of Psoriasis at a Tertiary Care Centre in North India: A Case Control Study

Satish Chand Sharma; Prafulla Kumar Sharma; R K Dudeja

Study of Association of Atherosclerotic Risk Factors and Metabolic Syndrome in Patients of Psoriasis at a Tertiary Care Centre in North India: A Case Control Study

J Assoc Physicians India. 2015 Sep;63(9):28-31.

Authors

Satish Chand Sharma¹, Prafulla Kumar Sharma², R K Dudeja³

Affiliations

¹ IIIrd Year Junior Resident.
² Professor and Head, Dept. of Dermatology.
³ Asstt. Professor, Dept.of Medicine, P.G.I.M.E.R. Dr. R.M.L. Hospital, New Delhi Received: 02.06.2014; Revised: 14.07.2014; Accepted: 22.07.2014.

PMID: 27608863

Abstract

Objective: To study the association between psoriasis and atherosclerotic risk factors, including metabolic syndrome.

Methods: Fifty patients with psoriasis and 50 controls were included in the study. Atherosclerotic risk factors were evaluated as per National Cholesterol Education Project Adult Treatment Panel III (NCEP-ATPIII). Metabolic syndrome was diagnosed as per South Asian Modified -National Cholesterol Education Programme's Adult Treatment Panel III (ATP III).

Results: Psoriatic patients had a significantly higher prevalence of hypertriglyceridaemia (≥150 mg/dl) (p=0.013), low HDL (< 40mg/dl) (p=0.025), impaired fasting blood glucose (≥100 mg/dl) (p=0.026). Metabolic syndrome was present in significant number of psoriasis patients than in controls [42 (28%) versus 9 (6%)] (P=0.009).

Conclusions: There is a significantly higher prevalence of metabolic syndrome and atherosclerotic risk factors in psoriasis patients as compared to controls.