Response to Comment on "Principles of connectivity among morphologically defined cell types in adult neocortex"

Science. 2016 Sep 9;353(6304):1108. doi: 10.1126/science.aaf6102.


The critique of Barth et al centers on three points: (i) the completeness of our study is overstated; (ii) the connectivity matrix we describe is biased by technical limitations of our brain-slicing and multipatching methods; and (iii) our cell classification scheme is arbitrary and we have simply renamed previously identified interneuron types. We address these criticisms in our Response.

Publication types

  • Comment

MeSH terms

  • Adult
  • Humans
  • Interneurons*
  • Neocortex*