Systematic review of motor evoked potentials monitoring during thoracic and thoracoabdominal aortic aneurysm open repair surgery: a diagnostic meta-analysis

J Anesth. 2016 Dec;30(6):1037-1050. doi: 10.1007/s00540-016-2242-x. Epub 2016 Sep 9.

Abstract

Motor evoked potential (MEP) monitoring has been used to prevent neurological complications such as paraplegia in patients who underwent thoracic or thoracoabdominal aortic aneurysm (TAA/TAAA) surgery. The object of this study was making a systematic review to survey the performance of MEP monitoring during TAA/TAAA open repair surgery. We searched electronic databases for relevant studies. We summarized the diagnostic data with summary sensitivity, summary specificity and forest plots of pooled sensitivity, and conducted sub-group analysis. The quality of the studies was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool. We also surveyed the reporting rate of clinical key factors such as methods of anesthesia, surgery, and success rate of MEP. Nineteen studies met our criteria. The results of meta-analysis showed 89.1 % summary sensitivity (95 % confidence interval 47.9-98.6 %) and 99.3 % summary specificity (95 % confidence interval 96.1-99.9 %). Sub-group analysis of pooled sensitivity and specificity by all-or-none cut-off point were better than other cut-off points. The results of the QUADAS-2 were not good. The performance of MEP monitoring was good for detecting postoperative paraplegia in TAA/TAAA open repair surgery. The cut-off point of all-or-none may be the best, according to our review.

Keywords: Diagnostic meta-analysis; Motor evoked potential (MEP) monitoring; Systematic review; TAAA open repair.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Aortic Aneurysm, Abdominal / surgery*
  • Aortic Aneurysm, Thoracic / surgery*
  • Evoked Potentials, Motor / physiology*
  • Humans
  • Nervous System Diseases / etiology
  • Paraplegia / etiology
  • Sensitivity and Specificity
  • Vascular Surgical Procedures / adverse effects
  • Vascular Surgical Procedures / methods