HTLV-I-associated myelopathy with adult T-cell leukemia

Neurology. 1989 Aug;39(8):1129-31. doi: 10.1212/wnl.39.8.1129.

Abstract

We report a 42-year-old Japanese woman with HTLV-I-associated myelopathy (HAM) combined with adult T-cell leukemia (ATL). Combination of the 2 diseases has been extremely rare. The infrequency is explained by HLA types unique to each disease. Our patient suggests that the HAM-associated HLA haplotype does not prevent the development of ATL.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibodies, Viral / analysis
  • Blotting, Southern
  • Chronic Disease
  • Diagnosis, Differential
  • Female
  • Haplotypes
  • Human T-lymphotropic virus 1 / immunology
  • Humans
  • Leukemia, T-Cell / complications*
  • Leukemia, T-Cell / diagnosis
  • Male
  • Middle Aged
  • Paraparesis, Tropical Spastic / complications*
  • Paraparesis, Tropical Spastic / diagnosis

Substances

  • Antibodies, Viral