Abstract
We report a 42-year-old Japanese woman with HTLV-I-associated myelopathy (HAM) combined with adult T-cell leukemia (ATL). Combination of the 2 diseases has been extremely rare. The infrequency is explained by HLA types unique to each disease. Our patient suggests that the HAM-associated HLA haplotype does not prevent the development of ATL.
MeSH terms
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Adult
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Antibodies, Viral / analysis
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Blotting, Southern
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Chronic Disease
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Diagnosis, Differential
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Female
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Haplotypes
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Human T-lymphotropic virus 1 / immunology
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Humans
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Leukemia, T-Cell / complications*
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Leukemia, T-Cell / diagnosis
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Male
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Middle Aged
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Paraparesis, Tropical Spastic / complications*
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Paraparesis, Tropical Spastic / diagnosis