Identification of further diversity among posaviruses

Arch Virol. 2016 Dec;161(12):3541-3548. doi: 10.1007/s00705-016-3048-8. Epub 2016 Sep 12.


Recently, there have been reports of new members of posavirus-like viruses in the order Picornavirales. In this study, using a metagenomics approach, 11 posavirus-like sequences (>7,000 nucleotides) were detected in 155 porcine fecal samples. Phylogenetic analysis revealed that the newly identified virus sequences, together with other posavirus-like viruses, form distinct clusters within the order Picornavirales, composed of eight genogroups and unassigned sequences based on amino acid sequences of the helicase and RNA-dependent RNA polymerase regions, with <40 % and <50 % sequence identity, respectively. We propose further classifications of highly diverse posavirus populations based on newly identified sequences from Japanese pig feces.

Keywords: Japan; Porcine feces; Posavirus; Sequence diversity.

MeSH terms

  • Animals
  • Cluster Analysis
  • Feces / virology*
  • Genetic Variation*
  • Metagenomics
  • Phylogeny
  • RNA Helicases / genetics
  • RNA Viruses / classification*
  • RNA Viruses / genetics*
  • RNA Viruses / isolation & purification
  • RNA-Dependent RNA Polymerase / genetics
  • Sequence Analysis, DNA
  • Sequence Homology
  • Swine / virology*


  • RNA-Dependent RNA Polymerase
  • RNA Helicases