Mycobacterium avium-intracellulare and the unpredictable course of hypercalcemia in an AIDS patient

Houriya Ayoubieh; Eyas Alkhalili

doi:10.1016/j.bjid.2016.08.002

Mycobacterium avium-intracellulare and the unpredictable course of hypercalcemia in an AIDS patient

Braz J Infect Dis. 2017 Jan-Feb;21(1):116-118. doi: 10.1016/j.bjid.2016.08.002. Epub 2016 Sep 15.

Authors

Houriya Ayoubieh¹, Eyas Alkhalili²

Affiliations

¹ University of New Mexico Health Sciences Centre, Albuquerque, NM, USA. Electronic address: hayoubieh@salud.unm.edu.
² University of New Mexico Health Sciences Centre, Albuquerque, NM, USA.

Abstract

A 37-year-old man with AIDS presented with altered mental status four weeks after stopping his medications for Mycobacterium avium-intracellulare (MAI). He had low CD4 cell count and severe hypercalcemia. Bone marrow biopsy revealed bone marrow infiltration by granulomas positive for acid-fast bacilli and cultures grew MAI. His hypercalcemia continued to worsen with the initiation of MAI therapy but we were able to treat it successfully with pamidronate and calcitonin.

Keywords: AIDS; Hypercalcemia; Mycobacterium infection.

Publication types

Case Reports

MeSH terms

AIDS-Related Opportunistic Infections / complications*
AIDS-Related Opportunistic Infections / microbiology
Adult
Bone Marrow / microbiology
Bone Marrow / pathology
CD4 Lymphocyte Count
Humans
Hypercalcemia / diagnostic imaging*
Hypercalcemia / drug therapy
Hypercalcemia / microbiology*
Magnetic Resonance Imaging
Male
Mycobacterium avium Complex / isolation & purification
Mycobacterium avium-intracellulare Infection / complications*