Heparin and Lovenox: What the Oral and Maxillofacial Surgeon Needs to Know

Oral Maxillofac Surg Clin North Am. 2016 Nov;28(4):507-513. doi: 10.1016/j.coms.2016.06.008. Epub 2016 Sep 10.


For the oral and maxillofacial surgeon, many patients will be on heparin products during surgery. So far, there is no standardized approach to treating anticoagulated patients during oral and maxillofacial surgical procedures. When a patient is on heparin therapy, heparin may be stopped 4 to 6 hours before surgery and resumed once hemostasis is achieved, usually within 24 hours. If low-molecular-weight heparin is administered, the treatment is generally stopped at least 12 hours before surgery and then resumed in a similar fashion. Local measures are generally enough to provide adequate hemostasis.

Keywords: Anticoagulation; Fondaparinux; Heparin; Lovenox; Protamine sulfate.

Publication types

  • Review

MeSH terms

  • Anticoagulants / administration & dosage*
  • Anticoagulants / therapeutic use
  • Enoxaparin / administration & dosage*
  • Enoxaparin / therapeutic use
  • Hemostasis, Surgical / methods*
  • Heparin / administration & dosage*
  • Heparin / therapeutic use
  • Humans
  • Medication Therapy Management
  • Oral Surgical Procedures*


  • Anticoagulants
  • Enoxaparin
  • Heparin