Mechanisms of auxin signaling

Development. 2016 Sep 15;143(18):3226-9. doi: 10.1242/dev.131870.


The plant hormone auxin triggers complex growth and developmental processes. Its underlying molecular mechanism of action facilitates rapid switching between transcriptional repression and gene activation through the auxin-dependent degradation of transcriptional repressors. The nuclear auxin signaling pathway consists of a small number of core components. However, in most plants each component is represented by a large gene family. The modular construction of the pathway can thus produce diverse transcriptional outputs depending on the cellular and environmental context. Here, and in the accompanying poster, we outline the current model for TIR1/AFB-dependent auxin signaling with an emphasis on recent studies.

Keywords: Auxin; Cellular response; Transcriptional response.

Publication types

  • Review
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Gene Expression Regulation, Plant / physiology
  • Indoleacetic Acids / metabolism*
  • Plant Growth Regulators / metabolism
  • Signal Transduction / physiology*


  • Indoleacetic Acids
  • Plant Growth Regulators