Objective: To report chronic central serous choroidopathy with severe visual loss in hyperopic microphthalmic identical twins.
Methods: The index patient was first examined in 1994, at age 31, and has been followed up closely for 17 years. He had repeated fluorescein and indocyanine green angiograms, OCT, ultrasound biometry, and recently also autofluorescence and EDI OCT. His twin brother was first examined in 2010, at age 47, and had a similar extensive exploration.
Results: The index patient had a mean refractive error of +6 D OU and VA was 20/32++ in the RE and 20/200 in the LE in 1994. Vision slowly went down to 20/800+ in the RE and 20/600 in the LE in 2011. His twin brother has a mean refractive error of +6 D OU and VA 20/400 OU. Both have a short axial length of the eye, a thick choroid with dilated vessels, and central serous choroidopathy with cystic degeneration of the macula and retina in the posterior pole.
Conclusions: We add to the reported complications of microphthalmos, chronic central serous choroidopathy.
Keywords: EDI OCT; autofluorescence imaging; central serous choroidopathy; fluorescein and indocyanine green angiography; hyperopia; identical twins; microphthalmos; nanophthalmos; posterior microphthalmos; short ocular axial length; thick choroid; ultrasound A-scan biometry.