Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Oct;24(5):714-729.
doi: 10.1111/1744-7917.12401. Epub 2016 Nov 24.

Effects and Mechanisms of Bacillus Thuringiensis Crystal Toxins for Mosquito Larvae

Affiliations
Review

Effects and Mechanisms of Bacillus Thuringiensis Crystal Toxins for Mosquito Larvae

Qi Zhang et al. Insect Sci. .

Abstract

Bacillus thuringiensis is a Gram-positive aerobic bacterium that produces insecticidal crystalline inclusions during sporulation phases of the mother cell. The virulence factor, known as parasporal crystals, is composed of Cry and Cyt toxins. Most Cry toxins display a common 3-domain topology. Cry toxins exert intoxication through toxin activation, receptor binding and pore formation in a suitable larval gut environment. The mosquitocidal toxins of Bt subsp. israelensis (Bti) were found to be highly active against mosquito larvae and are widely used for vector control. Bt subsp. jegathesan is another strain which possesses high potency against broad range of mosquito larvae. The present review summarizes characterized receptors for Cry toxins in mosquito larvae, and will also discuss the diversity and effects of 3-D mosquitocidal Cry toxin and the ongoing research for Cry toxin mechanisms generated from investigations of lepidopteran and dipteran larvae.

Keywords: Bacillus thuringiensis; Cry toxins; mode of action; mosquito; receptors.

Similar articles

See all similar articles

Cited by 6 articles

See all "Cited by" articles

Substances

LinkOut - more resources

Feedback