Comparison of BacT/Alert FAN and FAN Plus Bottles with Conventional Medium for Culturing Cerebrospinal Fluid

In Young Yoo; Sejong Chun; Dong Joon Song; Hee Jae Huh; Nam Yong Lee

doi:10.1128/JCM.01147-16

Comparison of BacT/Alert FAN and FAN Plus Bottles with Conventional Medium for Culturing Cerebrospinal Fluid

J Clin Microbiol. 2016 Nov;54(11):2837-2840. doi: 10.1128/JCM.01147-16. Epub 2016 Sep 14.

Authors

In Young Yoo¹, Sejong Chun¹, Dong Joon Song¹, Hee Jae Huh², Nam Yong Lee²

Affiliations

¹ Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
² Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea pmhhj77@gmail.com micro.lee@samsung.com.

Abstract

We compared the BacT/Alert system FAN and FAN Plus media to conventional media for culturing cerebrospinal fluid (CSF) with 2,545 samples. FAN/FAN Plus bottles showed better performance for isolating microorganisms in CSF than conventional media (positive rate, 7.2% [182/2,545] versus 3.1% [80/2,545]). The incremental recovery rate of Cryptococcus neoformans from FAN Plus bottles was higher than that from FAN bottles.

Publication types

Comparative Study
Evaluation Study

MeSH terms

Adult
Bacteria / isolation & purification*
Cerebrospinal Fluid / microbiology*
Culture Media / chemistry*
Fungi / isolation & purification*
Humans
Microbiological Techniques / methods*
Sensitivity and Specificity

Substances

Culture Media