Abstract
Liver failure is a disease with a high mortality rate. Often liver transplantation is the sole therapeutic option. On the one hand, liver support systems probably support the liver to allow regeneration, on the other hand they are an option to bridge for transplantation. This article gives an overview on the clinically used liver assist devices (molecular adsorbent recirculating system [MARS], Prometheus system, single-pass albumin dialysis [SPAD], plasmapheresis) and discusses the applications in liver failure.
© Georg Thieme Verlag Stuttgart · New York.
MeSH terms
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Blood Component Removal
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Combined Modality Therapy / methods
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Equipment Design
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Equipment Failure Analysis
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Evidence-Based Medicine
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Extracorporeal Circulation / instrumentation*
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Extracorporeal Circulation / methods
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Fluid Therapy / instrumentation
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Fluid Therapy / methods
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Humans
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Liver Failure / diagnosis
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Liver Failure / therapy*
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Liver Transplantation / instrumentation
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Liver Transplantation / methods
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Liver, Artificial*
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Peritoneal Dialysis / instrumentation
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Peritoneal Dialysis / methods*
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Plasmapheresis / instrumentation
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Plasmapheresis / methods*
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Renal Dialysis / instrumentation*
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Renal Dialysis / methods
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Serum Albumin / therapeutic use
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Treatment Outcome