3D Biomimetic Cultures: The Next Platform for Cell Biology

Trends Cell Biol. 2016 Nov;26(11):798-800. doi: 10.1016/j.tcb.2016.08.008. Epub 2016 Sep 13.

Abstract

Advances in engineering of cells and culture formats have led to the development of a new generation of 3D cultures that can recapitulate a variety of multicell-type, morphogenetic behaviors that were previously largely observable only in in vivo settings. Ultimately, these systems are likely to be assimilated into and forever change the landscape of biomedical research.

Keywords: in vitro models; organ on chip; organoids; organotypic; three dimensional.

MeSH terms

  • Animals
  • Biomimetics / methods*
  • Cell Biology*
  • Cell Culture Techniques / methods*
  • Humans
  • Models, Biological