Advances in engineering of cells and culture formats have led to the development of a new generation of 3D cultures that can recapitulate a variety of multicell-type, morphogenetic behaviors that were previously largely observable only in in vivo settings. Ultimately, these systems are likely to be assimilated into and forever change the landscape of biomedical research.
Keywords: in vitro models; organ on chip; organoids; organotypic; three dimensional.
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