Coronary angiography and failure to rescue after postoperative myocardial infarction in patients with coronary stents undergoing noncardiac surgery

Am J Surg. 2016 Nov;212(5):814-822.e1. doi: 10.1016/j.amjsurg.2016.07.023. Epub 2016 Aug 20.

Abstract

Background: We evaluated coronary angiography use among patients with coronary stents suffering postoperative myocardial infarction (MI) and the association with mortality.

Methods: Patients with prior coronary stenting who underwent inpatient noncardiac surgery in Veterans Affairs hospitals between 2000 and 2012 and experienced postoperative MI were identified. Predictors of 30-day post-MI mortality were evaluated.

Results: Following 12,096 operations, 353 (2.9%) patients had postoperative MI and 58 (16.4%) died. Post-MI coronary angiography was performed in 103 (29.2%) patients. Coronary angiography was not associated with 30-day mortality (odds ratio [OR]: .70, 95% CI: .35-1.42). Instead, 30-day mortality was predicted by revised cardiac risk index ≥3 (OR 1.91, 95% CI: 1.04-3.50) and prior bare metal stent (OR 2.12, 95% CI: 1.04-4.33).

Conclusions: Less than one-third of patients with coronary stents suffering postoperative MI underwent coronary angiography. Significant predictors of mortality were higher revised cardiac risk index and prior bare metal stent. These findings highlight the importance of comorbidities in predicting mortality following postoperative MI.

Keywords: Cardiac risk index; Coronary angiography; Coronary stent; Failure to rescue; Postoperative mortality; Postoperative myocardial infarction.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Cardiac Catheterization / methods
  • Comorbidity
  • Coronary Angiography / methods*
  • Coronary Disease / diagnosis
  • Coronary Disease / epidemiology
  • Coronary Disease / therapy
  • Female
  • Hospital Mortality*
  • Humans
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Myocardial Infarction / diagnostic imaging*
  • Myocardial Infarction / mortality
  • Myocardial Infarction / therapy
  • Odds Ratio
  • Postoperative Complications / diagnosis
  • Postoperative Complications / mortality
  • Postoperative Complications / therapy
  • Predictive Value of Tests
  • Retrospective Studies
  • Risk Assessment
  • Stents*
  • Surgical Procedures, Operative / adverse effects*
  • Surgical Procedures, Operative / methods
  • Survival Rate
  • Time Factors
  • Treatment Failure