Mitral valve repair facilitated with transapical beating heart NeoChord implantation in a non-Hodgkin's lymphoma patient

J Anesth. 2016 Dec;30(6):1056-1059. doi: 10.1007/s00540-016-2251-9. Epub 2016 Sep 19.


Elderly patients with severe hematological malignancies may require cardiac surgery. The combined impact of cardiopulmonary bypass (CPB) and surgical trauma is a potent inflammatory activator and is increased by intraoperative and postoperative complications. To avoid the adverse effects of CPB, minimally invasive off-pump techniques may be used in these patients. The transapical off-pump mitral valve intervention with NeoChord implantation (TOP-MINI) is a minimally invasive technique for mitral valve repair, which makes it possible to avoid the risks of CPB in selected patients, such as elderly, cancer or immunosuppressive patients. We report here the case of a 78-year-old male with B-cell non-Hodgkin's lymphoma, who presented with severe mitral regurgitation. The patient was successfully treated with the TOP-MINI procedure.

Keywords: Cardiac surgery; Minimal invasive; Mitral regurgitation; Non-Hodgkin’s lymphoma; Transapical mitral valve repair.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cardiac Surgical Procedures / methods
  • Cardiopulmonary Bypass
  • Heart Valve Prosthesis Implantation / methods
  • Humans
  • Lymphoma, Non-Hodgkin / pathology*
  • Male
  • Minimally Invasive Surgical Procedures / methods
  • Mitral Valve / surgery*
  • Mitral Valve Insufficiency / surgery*
  • Postoperative Complications / epidemiology
  • Treatment Outcome