Is it bowel-associated dermatosis-arthritis syndrome induced by small intestinal bacteria overgrowth?

Springerplus. 2016 Sep 13;5(1):1551. doi: 10.1186/s40064-016-3236-8. eCollection 2016.


Introduction: Bowel-associated dermatosis-arthritis syndrome is rare systemic diseases characterized by a prodrome of fever, chills, and influenza-like symptoms with subsequent skin eruptions, myalgias, and polyarthralgias. It is reported to be occurred in Intestinal bypass surgery and inflammatory bowel disease.

Case description: Herein, we described a 29-years-old man with Bowel-associated dermatosis-arthritis syndrome. He had no history of gastrointestinal surgery and inflammatory bowel disease. Distribution of the gut bacterial flora showed small intestinal bacterial overgrowth.

Discussion and evaluation: It is rarely form as Non-intestinal bypass road and non-inflammatory bowel disease was induced by small intestinal bacteria overgrowth.

Conclusions: We concluded that Immuno-inflammatory response to overgrowth of intestinal bacterial antigen induce the clinical symptoms of bowel-associated dermatosis-arthritis syndrome.

Keywords: Arthritis; Dermatosis; Inflammatory bowel disease.