Analyzing Confabulations in Schizophrenia and Healthy Participants

J Int Neuropsychol Soc. 2016 Oct;22(9):911-919. doi: 10.1017/S1355617716000801. Epub 2016 Sep 22.

Abstract

Objectives: Confabulations occur in schizophrenia and certain severe neuropsychiatric conditions, and to a lesser degree in healthy individuals. The present study used a forced confabulation paradigm to assess differences in confabulation between schizophrenia patients and healthy controls.

Methods: Schizophrenia patients (n=60) and healthy control participants (n=19) were shown a video with missing segments, asked to fill in the gaps with speculations, and tested on their memory for the story. Cognitive functions and severity of symptoms were also evaluated.

Results: Schizophrenia patients generated significantly more confabulations than healthy control participants and had a greater tendency to generate confabulations that were related to each other. Schizophrenic confabulations were positively associated with temporal context confusions and formal thought disorder, and negatively with delusions.

Conclusions: Our findings show that the schizophrenia patients generate more confabulations than healthy controls and schizophrenic confabulations are associated with positive symptoms. (JINS, 2016, 22, 911-919).

Keywords: False memory; Healthy controls; Psychiatry; Psychopathology; Psychosis; Severe mental illness.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Delusions / complications
  • Delusions / physiopathology*
  • Female
  • Humans
  • Male
  • Memory Disorders / etiology
  • Memory Disorders / physiopathology*
  • Middle Aged
  • Schizophrenia / complications
  • Schizophrenia / physiopathology*