Serratiopeptidase - A Cause for Spread of Infection

J Clin Diagn Res. 2016 Aug;10(8):ZD31-2. doi: 10.7860/JCDR/2016/21388.8302. Epub 2016 Aug 1.


Serratiopeptidase is a proteolytic enzyme that has been used for reducing inflammation, it has antiedemic, analgesic, fibrinolytic and caesinolytic properties. Serratiopeptidase is often used in oral surgery for its anti-inflammatory purpose after impaction surgery, maxillofacial trauma and infections but its use should be limited in cases of abscess due to its fibrinolytic activity. Here, we report a case of a buccal space abscess which had spread into deeper muscular layers after serratiopeptidase administration in a 32-year-old male without any systemic condition. Patient presented with a painful swelling on the right mid region of the face since seven days. Serratiopeptidase was discontinued. After routine blood investigation and ultrasonography, incision and drainage was done and the patient recovered after seven days of treatment.

Keywords: Abscess; Buccal space; Proteolytic enzyme.

Publication types

  • Case Reports