Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016;1490:163-76.
doi: 10.1007/978-1-4939-6433-8_10.

Experiment-Assisted Secondary Structure Prediction With RNAstructure

Affiliations

Experiment-Assisted Secondary Structure Prediction With RNAstructure

Zhenjiang Zech Xu et al. Methods Mol Biol. .

Abstract

Experimental probing data can be used to improve the accuracy of RNA secondary structure prediction. The software package RNAstructure can take advantage of enzymatic cleavage data, FMN cleavage data, traditional chemical modification reactivity data, and SHAPE reactivity data for secondary structure modeling. This chapter provides protocols for using experimental probing data with RNAstructure to restrain or constrain RNA secondary structure prediction.

Keywords: Chemical modification data; RNA structure prediction; SHAPE; Thermodynamics.

Similar articles

See all similar articles

Cited by 5 articles

Publication types

LinkOut - more resources

Feedback