Analytical progresses of the World Anti-Doping Agency Olympic laboratories: a 2016 update from London to Rio

Bioanalysis. 2016 Nov;8(21):2265-2279. doi: 10.4155/bio-2016-0185. Epub 2016 Sep 26.


The 2016 Olympic and Paralympic Games, the biggest event in human sports, was held in Rio de Janeiro with more than 10,500 athletes from 206 countries over the world competing for the highest of sports honors, an Olympic medal. With the hope that the Olympic ideal accompanies all aspects of the XXXI Olympiad, WADA accredited antidoping laboratories use the spearhead of analytical technology as a powerful tool in the fight against doping. This review summarizes the main analytical developments applied in antidoping testing methodology combined with the main amendments on the WADA regulations regarding analytical testing starting from the 2012 London Olympics until the 2016 Olympic Games in Rio de Janeiro.

Keywords: Olympic Games; SAR-PAGE; anabolic steroids; athlete biological passport; doping control; peptides.

Publication types

  • Review

MeSH terms

  • Anabolic Agents / analysis
  • Blood Transfusion
  • Chromatography, High Pressure Liquid
  • Doping in Sports*
  • Gas Chromatography-Mass Spectrometry*
  • Humans
  • International Agencies
  • Peptide Hormones / analysis
  • Performance-Enhancing Substances / analysis*
  • Tandem Mass Spectrometry*


  • Anabolic Agents
  • Peptide Hormones
  • Performance-Enhancing Substances