Capecitabine pharmacogenetics: historical milestones and progress toward clinical implementation

Pharmacogenomics. 2016 Oct;17(15):1607-1610. doi: 10.2217/pgs-2016-0133. Epub 2016 Sep 27.
No abstract available

Keywords: DPYD; TYMS; Xeloda; capecitabine; fluoropyrimidines; hand–foot syndrome; pharmacogenetics; ­thymidylate synthase.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / genetics
  • Breast Neoplasms / pathology
  • Capecitabine / pharmacokinetics
  • Capecitabine / therapeutic use*
  • Colorectal Neoplasms / drug therapy*
  • Colorectal Neoplasms / genetics
  • Colorectal Neoplasms / pathology
  • Female
  • Humans
  • Male
  • Pharmacogenetics / methods*
  • Thymidylate Synthase / genetics

Substances

  • Capecitabine
  • Thymidylate Synthase