Analysis of survival in patients with pulmonary atresia and intact ventricular septum treated surgically

Int J Cardiol. 1989 Aug;24(2):159-64. doi: 10.1016/0167-5273(89)90299-4.

Abstract

The epidemiology of 98 children who underwent surgical intervention for pulmonary atresia and intact ventricular septum is presented. Sixty-one (62.2%) of the children died. Survival time from the date of the first operation ranged from 0 to 17.76 years. Analysis of the survivors revealed that an estimate of the probability of surviving for two years is 47% (95% confidence limits of 37%, 57%). An estimate of the median survival time is 1.43 years. In a Cox proportional hazards model, using survival time in days as the outcome variable (n = 73, using complete data), operative weight at first operation (P = 0.0019), right/left ventricular pressure ratio (P = 0.0185), and absence of ventriculo-coronary arterial connections (P = 0.0362) were identified as significant predictors of survival.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Ductus Arteriosus, Patent / surgery*
  • Female
  • Follow-Up Studies
  • Hemodynamics
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Postoperative Complications / mortality*
  • Prostaglandins / administration & dosage
  • Pulmonary Artery / abnormalities*
  • Pulmonary Artery / surgery

Substances

  • Prostaglandins