Breast Cancer Epidemiology and Risk Factors

Clin Obstet Gynecol. 2016 Dec;59(4):651-672. doi: 10.1097/GRF.0000000000000239.


Between the years 2010 and 2012, the lifetime probability of developing female breast cancer was 12.3%, or approximately 1 in 8. Worldwide, breast cancer is the most common cancer in women. Survival is increasing. Between 2005 and 2011, the 5-year relative survival was found to be 89%. This is thought to be due to both the increase in utilization of population-wide screening, as well as advances in treatment. Less than 10% of breast cancers can be attributed to an inherited genetic mutation. Breast cancer is more commonly associated with environmental, reproductive, and lifestyle factors, some of which are potentially modifiable.

Publication types

  • Review

MeSH terms

  • Age Factors
  • Breast Neoplasms / classification
  • Breast Neoplasms / epidemiology*
  • Female
  • Humans
  • Incidence
  • Male
  • Pregnancy
  • Risk Factors