Identification of cryptic Candida species by MALDI-TOF mass spectrometry, not all MALDI-TOF systems are the same: focus on the C. parapsilosis species complex

Diagn Microbiol Infect Dis. 2016 Dec;86(4):385-386. doi: 10.1016/j.diagmicrobio.2016.08.028. Epub 2016 Sep 4.

Abstract

Data about the performance of MALDI-TOF mass spectrometry against cryptic Candida species are limited. According to our findings within the C. parapsilosis species complex, microbiologists should be aware that the choice of the instrument is critical for accurate species identification due to the risk of misidentification in the clinical setting.

Keywords: C. parapsilosis species complex; ITS sequencing; MALDI-TOF; Misidentification.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Candida / chemistry*
  • Candida / classification*
  • Candida / isolation & purification
  • Candidiasis / diagnosis*
  • Humans
  • Microbiological Techniques / methods*
  • Sensitivity and Specificity
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / instrumentation*
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods*