Fluency Tasks Generate Beta-Gamma Activity in Language-Related Cortical Areas of Patients During stereo-EEG Monitoring

Brain Lang. 2016 Dec;163:50-56. doi: 10.1016/j.bandl.2016.09.006. Epub 2016 Sep 28.

Abstract

A quantitative method was developed to map cortical areas responsive to cognitive tasks during intracerebral stereo-EEG recording sessions in drug-resistant patients candidate for epilepsy surgery. Frequency power changes were evaluated with a computer-assisted analysis in 7 patients during phonemic fluency tasks. All patients were right-handed and were explored with depth electrodes in the dominant frontal lobe. We demonstrate that fluency tasks enhance beta-gamma frequencies and reduce background activities in language network regions of the dominant hemisphere. Non-reproducible changes were observed in other explored brain areas during cognitive tests execution.

Keywords: Beta-gamma activity; Epilepsy surgery; Fluency tasks; Intracranial EEG; Stereo-EEG.

MeSH terms

  • Adolescent
  • Adult
  • Brain Mapping
  • Broca Area / physiology
  • Cerebral Cortex / physiology*
  • Electroencephalography*
  • Epilepsy / diagnosis
  • Epilepsy / physiopathology
  • Female
  • Frontal Lobe / physiology
  • Humans
  • Language*
  • Male