Mild Hypothermia in a Child with Low-Dose Risperidone

Z Kinder Jugendpsychiatr Psychother. 2017 Jul;45(4):335-337. doi: 10.1024/1422-4917/a000484. Epub 2016 Sep 29.


Risperidone is a widely used, second-generation antipsychotic approved for treating schizophrenia as well as for treating aggression in children and adolescents with mental retardation. The substance has a well-established risk profile including alterations of body temperature. Apart from hyperthermia with and without full-blown malignant neuroleptic syndrome, low body temperatures (hypothermia) have also been reported anecdotally, usually appearing in the context of comedication. Here, we report a case of hypothermia associated with a low-dose risperidone monotherapy in a child.

Keywords: antipsychotics; conduct disorder; hypothermia; risperidone; side effect.

Publication types

  • Case Reports

MeSH terms

  • Aggression / drug effects
  • Aggression / psychology
  • Attention Deficit Disorder with Hyperactivity / diagnosis
  • Attention Deficit Disorder with Hyperactivity / drug therapy*
  • Attention Deficit Disorder with Hyperactivity / psychology
  • Child
  • Cognitive Behavioral Therapy
  • Combined Modality Therapy
  • Comorbidity
  • Conduct Disorder / diagnosis
  • Conduct Disorder / drug therapy*
  • Conduct Disorder / psychology
  • Dose-Response Relationship, Drug
  • Humans
  • Hypothermia / chemically induced*
  • Hypothermia / diagnosis
  • Intellectual Disability / diagnosis
  • Intellectual Disability / drug therapy*
  • Intellectual Disability / psychology
  • Male
  • Risperidone / administration & dosage*
  • Risperidone / adverse effects*


  • Risperidone