Treatment of periorbital wrinkles using multipolar fractional radiofrequency in Korean patients

Lasers Med Sci. 2017 Jan;32(1):61-66. doi: 10.1007/s10103-016-2084-7. Epub 2016 Sep 30.


A limited number of studies have evaluated the efficacy and safety of electrode pin fractional radiofrequency (FRF) for periorbital wrinkle treatment in Asian patients, but none have measured noninvasive methodological objective parameters such as periorbital wrinkle area. This study aimed to investigate the efficacy and safety of electrode pin multipolar FRF for the improvement of periorbital wrinkles in Korean patients by using a noninvasive methodological objective parameter. Seventy female subjects with periorbital wrinkles (age range, 40-60 years) participated in this study. Each patient underwent three sessions of FRF treatment to the periorbital region separated by 2-week intervals. The area of periorbital wrinkles was analyzed by using a Robo Skin Analyzer CS50 at 4 weeks after the final treatment session. Periorbital wrinkle area was significantly decreased at 1-month follow-up (75.77 ± 29.46 mm2) compared to baseline (94.74 ± 31.62 mm2). The improvement ratio of periorbital wrinkle area was 20.02 %. Side effects were limited to transient mild erythema, swelling, and crusts. Pain was tolerable without local anesthesia. Our findings suggest that the multipolar electrode pin FRF can be an effective and safe method for reducing periorbital wrinkles in Asian patients.

Keywords: Asian; Fractional; Multipolar; Periorbital wrinkle; Radiofrequency.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Asian People*
  • Electrodes
  • Female
  • Humans
  • Male
  • Middle Aged
  • Orbit / radiation effects*
  • Patient Satisfaction
  • Radiofrequency Therapy*
  • Republic of Korea
  • Skin Aging / radiation effects*