Efficacy and safety of 5% minoxidil topical foam in male pattern hair loss treatment and patient satisfaction

Acta Dermatovenerol Alp Pannonica Adriat. 2016 Sep;25(3):41-44. doi: 10.15570/actaapa.2016.12.

Abstract

Introduction: Male pattern hair loss is widespread around the world. Its prevalence indicates the importance of finding the best treatment modalities. This study evaluates the efficacy and safety of minoxidil 5% topical foam in male pattern hair loss treatment and patient satisfaction.

Methods: This study was a before-and-after trial on 17 male patients with male pattern hair loss. Subjects were instructed to apply one capful (1 ml) of minoxidil 5% topical foam on the scalp daily for 6 months. Efficacy was assessed through hair counts, subject assessment, and global photographic review.

Results: Seventeen male volunteers were recruited, and three volunteers were withdrawn; 14 participated in the trial for 16 weeks, and 12 continued up to 24 weeks. The average hair count with a camera at week 16 (181.87 ± 52.42) and week 24 (194.58 ± 62.82) and with an eye count at week 16 (62.57 ± 15.28) and week 24 (69.91 ± 15.61) increased significantly compared to the baseline after intervention.

Conclusions: This study confirmed that minoxidil 5% topical foam is a safe and effective treatment for MPHL. The effect of it is evident after 24 weeks of use.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Administration, Topical
  • Adult
  • Alopecia / drug therapy*
  • Humans
  • Male
  • Middle Aged
  • Minoxidil / therapeutic use*
  • Patient Satisfaction
  • Treatment Outcome
  • Vasodilator Agents / therapeutic use*
  • Young Adult

Substances

  • Vasodilator Agents
  • Minoxidil