Retraction: "Cisplatin-induced antitumor activity is potentiated by the soy isoflavonen genistein in BxPC-3 pancreatic tumor xenografts" by Mohammad RM, Banerjee S, Li Y, Aboukameel A, Kucuk O, Sarkar FH. The above article, published in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement amongst the journal Editor in Chief, Fadlo R. Khuri; Wiley Periodicals, Inc.; and the American Cancer Society following an investigation by Wayne State University into the research activities of the second and last authors. The investigation found clear evidence that the 4-lane Rb bands for Figure 3A and Figure 4C are duplicated, manipulated, and re-labeled Rb bands. The investigation found no evidence that the 4-lane Rb bands correspond to the assays above them. The investigation further found that the 4-lane β-actin bands image in Figure 3B is a manipulated and re-labeled copy of the same β-actin bands image in Figure 5A of Int J Cancer. 2006 Apr 15;118(8):1930-6. The investigation committee concluded that this undermined the scientific basis of the publication, that no credible replacement data were available, and advised that the publication should be retracted.
References: Mohammad, R. M., Banerjee, S., Li, Y., Aboukameel, A., Kucuk, O. and Sarkar, F. H. (2006), Cisplatin-induced antitumor activity is potentiated by the soy isoflavone genistein in BxPC-3 pancreatic tumor xenografts. Cancer, 106: 1260-1268. doi: 10.1002/cncr.21731 Wang, Z., Zhang, Y., Banerjee, S., Li, Y. and Sarkar, F. H. (2006), Inhibition of nuclear factor κb activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells. Int. J. Cancer, 118: 1930-1936. doi: 10.1002/ijc.21589.
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