Influence of air pollution on exhaled carbon monoxide levels in smokers and non-smokers. A prospective cross-sectional study

Environ Res. 2017 Jan:152:496-502. doi: 10.1016/j.envres.2016.09.004. Epub 2016 Oct 4.

Abstract

Background: The poor air quality and cigarette smoking are the most important reasons for increased carbon monoxide (CO) level in exhaled air. However, the influence of high air pollution concentration in big cities on the exhaled CO level has not been well studied yet.

Objectives: To evaluate the impact of smoking habit and air pollution in the place of living on the level of CO in exhaled air.

Methods: Citizens from two large cities and one small town in Poland were asked to complete a survey disclosing their place of residence, education level, work status and smoking habits. Subsequently, the CO level in their exhaled air was measured. Air quality data, obtained from the Regional Inspectorates of Environmental Protection, revealed the differences in atmospheric CO concentration between locations.

Results: 1226 subjects were divided into 4 groups based on their declared smoking status and place of living. The average CO level in exhaled air was significantly higher in smokers than in non-smokers (p<0.0001) as well as in non-smokers from big cities than non-smokers from small ones (p<0.0001). Created model showed that non-smokers from big cities have odds ratio of 125.3 for exceeding CO cutoff level of 4ppm compared to non-smokers from small towns.

Conclusions: The average CO level in exhaled air is significantly higher in smokers than non-smokers. Among non-smokers, the average exhaled CO level is significantly higher in big city than small town citizens. These results suggest that permanent exposure to an increased concentration of air pollution and cigarette smoking affect the level of exhaled CO.

Keywords: Air pollution; Air quality; Exhaled carbon monoxide; Health risk assessment; Smoking cigarettes.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Air Pollutants / analysis*
  • Air Pollution / analysis
  • Breath Tests
  • Carbon Monoxide / analysis*
  • Cross-Sectional Studies
  • Exhalation
  • Female
  • Humans
  • Male
  • Middle Aged
  • Poland
  • Prospective Studies
  • Rural Population
  • Smoking*
  • Tobacco Smoke Pollution / analysis*
  • Urban Population
  • Young Adult

Substances

  • Air Pollutants
  • Tobacco Smoke Pollution
  • Carbon Monoxide