Pulmonary tumor diagnosed as an undifferentiated sarcoma with epithelioid features: a case report

J Med Case Rep. 2016 Oct 3;10(1):274. doi: 10.1186/s13256-016-1056-7.

Abstract

Background: Pulmonary sarcomas are uncommon accounting for 0.5 % of all primary lung cancers. Undifferentiated sarcomas account for up to 20 % of soft tissue sarcomas. A lung tumor revealed to be an undifferentiated sarcoma with epithelioid features has never been reported in the literature.

Case presentation: A 61-year-old white Moroccan man presented with 2 months' history of hemoptysis and dyspnea. Chest computed tomography showed a cystic mass involving the lower field of his right lung evoking first a hydatid cyst. Abdominal computed tomography revealed bilateral adrenal nodules. Surgical resection of the lung mass was performed. On pathological examination, the tumor was cystic containing necrotic material. A histological diagnosis of undifferentiated sarcoma with epithelioid features was made. A positron emission tomography scan showed involvement of his pleura, left colon, adrenal glands, left thigh muscle, and leptomeninges.

Conclusions: Undifferentiated sarcoma with epithelioid features is a rare malignant mesenchymal tumor. Clinical and radiological features are not specific. A differential diagnosis includes sarcomatoid carcinoma, malignant mesothelioma, melanoma, and other epithelioid sarcomas.

Keywords: Epithelioid; Lung; Sarcoma; Undifferentiated.

Publication types

  • Case Reports

MeSH terms

  • Biomarkers, Tumor
  • Diagnosis, Differential
  • Dyspnea / diagnostic imaging*
  • Dyspnea / etiology
  • Hemoptysis / diagnostic imaging*
  • Hemoptysis / etiology
  • Humans
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / pathology*
  • Lung Neoplasms / surgery
  • Male
  • Middle Aged
  • Positron-Emission Tomography*
  • Sarcoma / diagnostic imaging
  • Sarcoma / pathology*
  • Sarcoma / surgery
  • Tomography, X-Ray Computed*
  • Treatment Outcome

Substances

  • Biomarkers, Tumor