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. 2016 Oct 11;52(83):12330-12333.
doi: 10.1039/c6cc05880a.

An Efficient Two-Photon Fluorescent Probe for Monitoring Mitochondrial Singlet Oxygen in Tissues During Photodynamic Therapy

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An Efficient Two-Photon Fluorescent Probe for Monitoring Mitochondrial Singlet Oxygen in Tissues During Photodynamic Therapy

Hong-Wen Liu et al. Chem Commun (Camb). .

Abstract

A promising two-photon fluorescent probe MNAH for detecting 1O2 during the PDT process in mitochondria was proposed for the first time. MNAH was successfully applied for two-photon imaging of 1O2 in living cells and tissues during the PDT process with deep-tissue imaging depth. MNAH can be a powerful molecular tool for studying 1O2 generation in mitochondria during the PDT process.

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