Miller Fisher syndrome

BMJ Case Rep. 2016 Oct 13:2016:bcr2016217085. doi: 10.1136/bcr-2016-217085.

Abstract

A man aged 30 years presented to the emergency department (ED) with ataxia, areflexia, facial weakness, ophthalmoplegia, extremity weakness and back pain for 4 days. 4 days prior to attending the ED, the patient had suffered from diarrhoea for 2 weeks. The diagnosis of Miller Fisher syndrome was performed on the dual basis of clinical features in addition to an investigations report. Nerve conduction studies and anti-GQ1b IgG antibody analysis were requested. Once IgA deficiency was ruled out, the patient was started on intravenous immunoglobulin (400 mg/kg/day).

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Gangliosides / immunology
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulins, Intravenous / therapeutic use*
  • Male
  • Miller Fisher Syndrome / diagnosis
  • Miller Fisher Syndrome / therapy*

Substances

  • Gangliosides
  • Immunoglobulin G
  • Immunoglobulins, Intravenous
  • GQ1b ganglioside