Thyroid Dysfunction and Male Reproductive Physiology

Semin Reprod Med. 2016 Nov;34(6):356-360. doi: 10.1055/s-0036-1593491. Epub 2016 Oct 14.

Abstract

Normal thyroid physiology is paramount for the proper development and important for the maintenance of male reproduction. Both short- and long-term deviations in thyroid hormone levels have been shown to alter male reproductive function on a micro- and macroscopic level. Thyrotoxicosis and hypothyroidism are associated with changes in spermatogenesis, semen quality, levels of sexual hormones, and erectile function. However, the degree to which thyroid dysfunction is clinically responsible for male infertility has not been clearly elucidated.

Publication types

  • Review

MeSH terms

  • Humans
  • Hypothalamus
  • Infertility, Male / complications
  • Infertility, Male / physiopathology*
  • Male
  • Reproduction*
  • Semen Analysis
  • Spermatogenesis
  • Thyroid Diseases / complications
  • Thyroid Diseases / physiopathology*
  • Thyroid Gland / physiology*
  • Thyrotropin-Releasing Hormone / blood

Substances

  • Thyrotropin-Releasing Hormone