Abstract
The 1999 cessation of vaccination against adenovirus types 4 and 7 among US Army trainees resulted in reemergence of acute respiratory disease (ARD) outbreaks. The 2011 implementation of a replacement vaccine led to dramatic and sustained decreases in ARD cases, supporting continuation of vaccination in this population at high risk for ARD.
Keywords:
ARD; US Army trainees; acute respiratory disease; adenovirus; basic training; disease rates; dynamic population; high-risk population; initial entry training; military; outbreaks; vaccination; vaccine; viruses.
MeSH terms
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Acute Disease
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Adenovirus Infections, Human / epidemiology
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Adenovirus Infections, Human / immunology
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Adenovirus Infections, Human / prevention & control*
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Adenovirus Infections, Human / virology
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Adenovirus Vaccines
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Adenoviruses, Human / immunology
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Adenoviruses, Human / pathogenicity
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Disease Outbreaks / prevention & control*
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Disease Outbreaks / statistics & numerical data
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Humans
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Immunization Programs / organization & administration*
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Immunization Schedule
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Military Personnel*
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Respiratory Tract Infections / epidemiology
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Respiratory Tract Infections / immunology
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Respiratory Tract Infections / prevention & control*
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Respiratory Tract Infections / virology
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United States / epidemiology
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Vaccination / methods*