Medical nutrition therapy for pregnant women with gestational diabetes mellitus-A retrospective cohort study

Taiwan J Obstet Gynecol. 2016 Oct;55(5):666-671. doi: 10.1016/j.tjog.2016.01.005.

Abstract

Objective: Women diagnosed with gestational diabetes mellitus (GDM) remain at high risk of developing type 2 diabetes mellitus in the future. The effectiveness of medical nutrition therapy (MNT) acting on GDM is increasingly becoming noteworthy.

Materials and methods: A retrospective cohort study involving 488 GDM cases was conducted. The prepregnancy weight, weight changes during pregnancy, glucose levels, GDM management, follow-up, and birth outcomes were recorded from 2008 to 2012.

Results: Overall, 62.91% of the women received MNT, with an increasing trend from 2008 to 2012 (p < 0.01). The fasting plasma glucose, 2-hour blood glucose, and weight gain at 28 weeks, 32 weeks, and 36 weeks as well as intrapartum were lower in the MNT group than in the non-MNT group. Total weight gain during pregnancy and the rates of adverse events during pregnancy were lower in the MNT group compared to the non-MNT group (all p < 0.05). Moreover, 92.2% of the participants in the MNT group had a normal oral glucose tolerance test result, and the rate of exclusive breastfeeding within 4 months after delivery was 54.4% in the MNT group; both were higher than those of the non-MNT group (66.3%, p < 0.001; 29.3%, p < 0.05).

Conclusion: MNT can reduce the incidence of pregnancy complications, increase the exclusive breastfeeding rate, and improve pregnancy outcomes.

Keywords: gestational diabetes mellitus; glucose; medical nutrition therapy; outcome.

MeSH terms

  • Adult
  • Blood Glucose / metabolism*
  • Diabetes, Gestational / blood
  • Diabetes, Gestational / therapy*
  • Female
  • Follow-Up Studies
  • Glucose Tolerance Test
  • Humans
  • Nutrition Therapy / methods*
  • Pregnancy
  • Pregnancy Outcome
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult

Substances

  • Blood Glucose